The Power of Psychedelic Therapy and the Mind-Gut Connection | Emeran Mayer, MD

On this episode, we are joined by renowned Gastroenterologist, Neuroscientist, and Distinguished Research Professor, Emeran A Mayer, as he delves into the fascinating world of psychedelic therapy, the mind-gut connection, and the crucial link between mental and physical health. In this thought-provoking episode, Dr. Mayer presents a balanced and evidence-based exploration of the power and potential of psychedelic therapy, while emphasizing the importance of responsible usage without hyperbole. Drawing upon his extensive expertise in gastroenterology and neuroscience, Dr. Mayer sheds light on the profound impact that psychedelic substances can have on our mental well-being and the intricate relationship between our brain and gut. Whether you are a healthcare professional, researcher, or simply curious about the potential of psychedelic therapy, this discussion with Emeran A Mayer will expand your understanding and inspire further exploration into this evolving field.

0:00 Intro

2:38 Discovering The Mind-Gut Connection

9:53 Finding the Link Between Mental Health and Physical

16:23 Honoring the Fullness of Who we Are

24:00 Experiencing Synchronicity & Psychedelics

30:04 Dr. Mayer’s First Experience with Ketamine

41:43 Sitting with Psilocybin Mushrooms

45:03 Preventing Hyperbole & Using Responsibly

51:22 The Mystery of Psychedelics

56:11 Learn More About Mind-Gut Connection

59:18 Conclusion

Emeran A Mayer is a Gastroenterologist, Neuroscientist and Distinguished Research Professor in the Department of Medicine at the David Geffen School of Medicine at UCLA, the Executive Director of the G. Oppenheimer Center for Neurobiology of Stress & Resilience and Founding Director of the Goodman Luskin Microbiome Center at UCLA. He is one of the pioneers and leading researchers in the bidirectional communication within the brain gut microbiome system with wide-ranging applications in intestinal and brain disorders. He has published 415 scientific papers, co edited 3 books and has an h-index of 125. He published the best selling books The Mind Gut Connection in 2016, the Gut Immune Connection in June 2021, and the recipe book Interconnected Plates in 2023. He is currently working on a MasterClass and a PBS documentary about the mind gut immune connection. He is the recipient of numerous awards, including the 2016 David McLean award from the American Psychosomatic Society and the 2017 Ismar Boas Medal from the German Society of Gastroenterology and Metabolic Disease.

Dr. Mayer’s website:

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Drew Ramsey, MD

Drew Ramsey, M.D. is a psychiatrist, author, and farmer. He is a clear voice in the mental health conversation and one of psychiatry’s leading proponents of using nutritional interventions. He is an assistant clinical professor of psychiatry at Columbia University College of Physicians and Surgeons.

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